A graph-based approach for proteoform identification and quantification using top-down homogeneous multiplexed tandem mass spectra

Abstract Background Top-down homogeneous multiplexed tandem mass (HomMTM) spectra are generated from modified proteoforms of the sara stedy stand aid same protein with different post-translational modification patterns.They are frequently observed in the analysis of ultramodified proteins, some proteoforms of which have similar molecular weights an

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